Colon cancer: Changes in gut bacteria may lead to new blood test
Clinical Gastroenterology Journal is a peer reviewed, open access journal considering submissions on topics covering on all aspects of digestive system, gastrointestinal diseases, liver, bilary tract, pancreas, diseases of related organs Ulcer medicine, Colitis, Diverticulitis and associated disorders and their treatment.
Research in mice and humans suggests that imbalances in gut bacteria could play a key role in promoting the development of colorectal cancer. The finding is helping researchers develop a blood test that may help them diagnose this form of cancer.
In 2019, doctors will have diagnosed an estimated 145,600 new cases of colorectal cancer in the United States alone, according to the National Cancer Institute. his form of cancer has no obvious symptoms in its initial stages, which can make it hard to diagnose early on. This may mean that individuals do not have the opportunity to start the appropriate treatment before the tumors have grown and spread.
Matters become even more complicated in the case of sporadic colorectal cancer, which develops in people with no known risk factors for cancer.
For these reasons, researchers are continually looking for better ways of understanding both what drives colorectal cancer risk, and how to identify its presence early on.
This finding has helped the investigators develop a blood test able to pick up on the epigenetic (gene expression) changes that, in turn, are associated with both dysbiosis and tumor development.
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