The Need for Improvements in Ultratrace Analysis for Biological and Environmental Analysis


Analytical chemists continue to develop methods for ultratrace-level analyses that are used by practitioners in areas such as environmental, human health studies, and process technology. However, questions continue to arise about whether the current methods are adequate. Global challenges that point to the need for significant disruptive technology in analytical chemistry should be addressed. For example, Endocrine disruptors either mimic or block the production of naturally occurring hormones. Compounds known to be endocrine disruptors include parabens, triclosan, polychlorinated biphenyls, bisphenol A, dioxin, flame retardants, plasticizers, and some pharmaceuticals. For many of these compounds, the minimum concentration level that will not affect the endocrine systems is not yet known. Similarly, oxidative stress on humans and wildlife because of exposure to ultratrace levels of pollutants is also of significant concern. Oxidative stress is suspected in neurodegenerative diseases such as Alzheimer’s disease, Parkinson’s disease, and multiple sclerosis.

Current analytical devices are not meeting all of the needs for ultratrace-level detection as described above. We must develop new means to lower the detection limits of organic and biological compounds. Clearly, further improvements in preconcentration capabilities with solid-phase extraction (SPE) and in chromatographic efficiency must occur. These improvements will facilitate improved detection limits for the analysis of small to medium organic compounds. In addition, MS detection limit improvements are needed. Analytical chemists must push forward to move detection limits lower and continue to improve the selectivity of analyses.

The Journal of Chromatography & Separation Techniques aims to disseminate knowledge and promote discussion through the publication of peer-reviewed, high quality research papers on all topics related to Chromatography emphasizing on improvements in Ultratrace Analysis.

The Journal covers high-level research education and development related to wide range of subjects including pharmaceutical, environmental, food and clinical sciences, reaching out to analytical scientists worldwide. Original research articles, reviews, short communications, and letters to the editors in the fields of chromatography and separation science are accepted. Every effort is made to have a quality, rigorous, critical peer-review and rapid publishing process.

Realizing the importance of this field, OMICS Group is organizing prestigious conferences worldwide. The Conferences will provide a great scope for interaction of professionals including biochemistry experts, top-level biotechnologists and analytical chemistry scientists from around the globe, on a single platform.

On behalf of the Journal of Chromatography & Separation Techniques, as Editor-In-Chief it is my great pleasure and honor to welcome you to the journal and inform you that, it’s been ten long years since we have started the journal, now we are celebrating the 10th Anniversary and we are privileged to welcome Analytical scientific community from around the globe to our journal.

Submit your manuscripts online to publish with us. For further information or assistance in this regard E-mail your queries at




Associate Managing Editor

Journal of Chromatography & Separation Techniques


WhatsApp: +3225889658